On March 15, 1963, the all-white Mississippi State basketball team snuck out of its home state, defying a court injunction prohibiting the team from competing against black players. The team traveled to East Lansing, Michigan to play Loyola (Chicago) helping in part to end segregation in college sports. Loyola won the game 61-51, and went on to win the national championship.
Source : Detroit Free Press, August 3, 2012.
For another article, see Jerry Green, “Before the Madness, an NCAA Tournament game that truly mattered”, Detroit News, March 15, 2013.